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The Wasp System: An open source environment for managing and analyzing genomic data
Abstract The challenges associated with the managemThe challenges associated with the management, analysis and interpretation of assays based on massively-parallel sequencing (MPS) are both individually complex and numerous. We describe what we believe to be the appropriate solution, one that represents a departure from traditional computational biology approaches. The Wasp System is an open source, distributed package written in Spring/J2EE that creates a foundation for development of an end-to-end solution for MPS-based experiments or clinical tests. Recognizing that one group will be unable to solve these challenges in isolation, we describe a nurtured open source development model that will allow the software to be collectively used, shared and developed. The ultimate goal is to emulate resources such as the Virtual Observatory of the astrophysics community, enabling computationally-inexpert scientists and clinicians to explore and interpret their MPS data. Here we describe the current implementation and development of the Wasp System and the roadmap for its community development.the roadmap for its community development.
Abstractsub The challenges associated with the managemThe challenges associated with the management, analysis and interpretation of assays based on massively-parallel sequencing (MPS) are both individually complex and numerous. We describe what we believe to be the appropriate solution, one that represents a departure from traditional computational biology approaches. The Wasp System is an open source, distributed package written in Spring/J2EE that creates a foundation for development of an end-to-end solution for MPS-based experiments or clinical tests. Recognizing that one group will be unable to solve these challenges in isolation, we describe a nurtured open source development model that will allow the software to be collectively used, shared and developed. The ultimate goal is to emulate resources such as the Virtual Observatory of the astrophysics community, enabling computationally-inexpert scientists and clinicians to explore and interpret their MPS data. Here we describe the current implementation and development of the Wasp System and the roadmap for its community development.the roadmap for its community development.
Bibtextype article  +
Doi 10.1016/j.ygeno.2012.08.005  +
Has author McLellan A.S. + , Dubin R.A. + , Jing Q. + , Broin P.T. + , Moskowitz D. + , Suzuki M. + , Calder R.B. + , Hargitai J. + , Golden A. + , Greally J.M. +
Has extra keyword Analytic method + , Article + , Biology + , Chromatin immunoprecipitation + , Computer program + , Documentation + , Ecosystem + , Epigenetics + , Genetic database + , Genomics + , Information processing + , Information system + , Massively parallel sequencing + , Physics + , Priority journal + , Process development + , Process optimization + , RNA sequence + , Workflow + , Computer Communication Networks + , Database Management Systems + , Genome + , Human + , High-Throughput Nucleotide Sequencing + , Humans + , Tool +
Has keyword Database + , Distributed + , LIMS + , Massively-parallel sequencing + , Open source + , Workflow +
Issn 8887543  +
Issue 6  +
Language English +
Number of citations by publication 0  +
Number of references by publication 0  +
Pages 345–351  +
Published in Genomics +
Pubmed 22944616  +
Title The Wasp System: An open source environment for managing and analyzing genomic data +
Type journal article  +
Volume 100  +
Year 2012 +
Creation dateThis property is a special property in this wiki. 8 November 2014 04:17:33  +
Categories Publications without license parameter  + , Publications without remote mirror parameter  + , Publications without archive mirror parameter  + , Publications without paywall mirror parameter  + , Journal articles  + , Publications without references parameter  + , Publications  +
Modification dateThis property is a special property in this wiki. 8 November 2014 04:17:33  +
DateThis property is a special property in this wiki. 2012  +
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